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VOLUME 33, ISSUE 06

PHYSIOLOGICAL SLEEPINESS AND MOTOR VEHICLE CRASHES
The 10-Year Risk of Verified Motor Vehicle Crashes in Relation to Physiologic Sleepiness

Christopher Drake, PhD1; Timothy Roehrs, PhD1; Naomi Breslau, PhD2; Eric Johnson, PhD3; Catherine Jefferson, BS1; Holly Scofield, RN1; Thomas Roth, PhD1

1Henry Ford Hospital Sleep Disorders and Research Center, Detroit, MI; 2Department of Epidemiology, Michigan State University, East Lansing, MI; 3Behavioral Health Epidemiology Program, Research Triangle Institute International, Research Triangle Park, NC



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Study Objectives: The purpose of this study was to determine the risk of DMV documented crashes as a function of physiological sleepiness in a population-based sample.
Design: 24-hour laboratory assessment (nocturnal polysomnogram and daytime MSLT) and 10-year crash rate based on DMV obtained accident records.
Participants: 618 individuals (mean age = 41.6 ± 12.8; 48.5% male) were recruited from the general population of southeastern Michigan using random-digit dialing techniques.
Results: Subjects were divided into 3 groups based on their average MSLT latency (in minutes) as follows: excessively sleepy, 0.0 to ≤ 5.0 (n = 69); moderately sleepy, 5.0 to ≤ 10.0 (n = 204); and alert, > 10 (n = 345). Main outcome measures were DMV data on accidents from 1995-2005. Rates for all accidents in the 3 MSLT groups were: excessively sleepy = 59.4%, moderately sleepy = 52.5%, alert = 47.3%. Excessively sleepy subjects were at significantly greater risk of an accident over the 10-year period compared to alert subjects. A similar relation was observed when we limited the database to those accident victims with severe injury (excessively sleepy = 4.3%, moderately sleepy = 0.5%, alert = 0.6%; P = 0.028). When the victim was the only occupant of the car, subjects in the lowest MSLT group (highest sleepiness) had the greatest crash rate compared with alert individuals (excessively sleepy = 52.2%, moderately sleepy = 42.2%, alert = 37.4%; P = 0.022).
Interventions: N/A
Conclusions: These data demonstrate that the MSLT, a physiological measure of sleepiness, is predictive of an increased risk of DMV documented automotive crashes in the general population.
Keywords: Excessive sleepiness, fatigue, general population, accidents, crashes, multiple sleep latency test

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